Cardiovascular and metabolic consequences of obesity

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Cardiovascular and metabolic consequences of obesity

INTRODUCTION The alarming increase in the incidence and impact of obesity in Australia requires urgent national focus at all levels of government and the community. The reason for the call to action has been due to the realization of the enormity of the health issues of being overweight or obese. There is clearly increased risk of metabolic disease, cardiovascular complications and premature de...

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Metabolic consequences of childhood obesity.

153 Lifestyle changes are among the many factors influencing the growing epidemic of childhood obesity worldwide, as this age group spends more time on computers, inactive, and have more access to ‘fast food’. Based on International Obesity Task Force (IOTF) criteria, the prevalence of overweight and obesity in school-age children has increased in all regions of the world, from 2000 to 2010 (Fi...

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Obesity, metabolic syndrome, and cardiovascular disease.

Early childhood overweight and obesity have alarmingly increased over the years. Adulthood obesity is a well demonstrated significant independent predictor of cardiovascular risk (CVR) and/or mortality, which predisposes to the major components of metabolic syndrome (MS). Evidence of MS in obese children has been also reported associated with biochemical and inflammatory factors that affect vas...

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Adverse metabolic and cardiovascular consequences of circadian misalignment.

There is considerable epidemiological evidence that shift work is associated with increased risk for obesity, diabetes, and cardiovascular disease, perhaps the result of physiologic maladaptation to chronically sleeping and eating at abnormal circadian times. To begin to understand underlying mechanisms, we determined the effects of such misalignment between behavioral cycles (fasting/feeding a...

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The perfect storm: obesity, adipocyte dysfunction, and metabolic consequences.

BACKGROUND As the prevalence of adiposity soars in both developed and developing nations, appreciation of the close links between obesity and disease increases. The strong relationships between excess adipose tissue and poor health outcomes, including cardiovascular disease, diabetes, and cancer, mandate elucidation of the complex cellular, hormonal, and molecular pathophysiology whereby adipos...

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ژورنال

عنوان ژورنال: Frontiers in Physiology

سال: 2015

ISSN: 1664-042X

DOI: 10.3389/fphys.2015.00032